Narahara Chari D.

Narahara Chari D.

Metro Jacksonville
30K followers 500+ connections

Services

Experience

  • Deutsche Bank Graphic

    Deutsche Bank

    New York, New York

  • -

    Short Hills, New Jersey

  • -

    Newark, New Jersey

  • -

    Hopkinton, MA

  • -

    Cambridge, MA

  • -

    Cambridge, MA

  • -

    Hudson, NH

Education

Licenses & Certifications

  • Chief Data Officer Graphic

    Chief Data Officer

    Collibra

    Issued
  • Finance Foundational Series - Enterprise Overview and Corporate Finance Strategy Graphic

    Finance Foundational Series - Enterprise Overview and Corporate Finance Strategy

    Prudential Financial

    Issued
  • Advanced Methods in Data Science and Big Data Analytics

    Dell EMC

    Issued
  • Data Science and Big Data Analytics

    Dell EMC

    Issued
  • Changing the Culture - Teaching for Inclusion (Teaching Students with Disabilities) Graphic

    Changing the Culture - Teaching for Inclusion (Teaching Students with Disabilities)

    University of Rhode Island

    Issued
  • From Fourier Series to Wavelets - Theory and Applications by The School of Mathematics and Statistics Graphic

    From Fourier Series to Wavelets - Theory and Applications by The School of Mathematics and Statistics

    University of Hyderabad

    Issued
  • Graduate Aptitude Test in Engineering (GATE) Graphic

    Graduate Aptitude Test in Engineering (GATE)

    Government of India

    Issued Expires

Volunteer Experience

Publications

  • Development and comparative assessment of Raman spectroscopic classification algorithms for lesion discrimination in stereotactic breast biopsies with microcalcifications

    Journal of Biophotonics

    Microcalcifications are an early mammographic sign of breast cancer and a target for stereotactic breast needle biopsy. Here, we develop and compare different approaches for developing Raman classification algorithms to diagnose invasive and in situ breast cancer, fibrocystic change and fibroadenoma that can be associated with microcalcifications. In this study, Raman spectra were acquired from tissue cores obtained from fresh breast biopsies and analyzed using a constituent-based breast model.…

    Microcalcifications are an early mammographic sign of breast cancer and a target for stereotactic breast needle biopsy. Here, we develop and compare different approaches for developing Raman classification algorithms to diagnose invasive and in situ breast cancer, fibrocystic change and fibroadenoma that can be associated with microcalcifications. In this study, Raman spectra were acquired from tissue cores obtained from fresh breast biopsies and analyzed using a constituent-based breast model. Diagnostic algorithms based on the breast model fit coefficients were devised using logistic regression, C4.5 decision tree classification, k-nearest neighbor (k -NN) and support vector machine (SVM) analysis, and subjected to leave-one-out cross validation. The best performing algorithm was based on SVM analysis (with radial basis function), which yielded a positive predictive value of 100% and negative predictive value of 96% for cancer diagnosis. Importantly, these results demonstrate that Raman spectroscopy provides adequate diagnostic information for lesion discrimination even in the presence of microcalcifications, which to the best of our knowledge has not been previously reported. (© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

    See publication

Patents

  • Systems and methods for sampling calibration of non-invasive analyte measurements

    Issued US US20170127983A1

    Systems and methods of the present invention provide a calibration model that requires minimal information compared with prior techniques. These systems and methods represent the first generalized approach for combined treatment of spectroscopic measurements of a dynamic, mass transfer system
    with the underlying kinetic model of said system. The technique can be applied to non-invasive glucose monitoring or monitoring of chemical reaction dynamics.

    See patent
  • Raman spectroscopy for detection of glycated analytes

    Issued US 20140349337

    The present invention relates to the optical measurement of blood analytes, such as glycated hemoglobin (HbA1c) and serum albumin as a functional metric of mean blood glucose in the diagnosis of diabetic patients. Non-enhanced Raman spectroscopy is employed as the analytical method for quantitative detection of blood analytes. Using processing techniques, non-enzymatic glycosylation (glycation) of the analytes results in measurable and highly reproducible changes in the acquired spectral data…

    The present invention relates to the optical measurement of blood analytes, such as glycated hemoglobin (HbA1c) and serum albumin as a functional metric of mean blood glucose in the diagnosis of diabetic patients. Non-enhanced Raman spectroscopy is employed as the analytical method for quantitative detection of blood analytes. Using processing techniques, non-enzymatic glycosylation (glycation) of the analytes results in measurable and highly reproducible changes in the acquired spectral data, which enable the accurate measurements and classification of glycated and unglycated analytes.

    See patent
  • Portable optical fiber probe-based spectroscopic scanner for rapid cancer diagnosis

    Issued US US20120302892 A1

    A multimodal probe system for spectroscopic scanning of tissue for disease diagnosis. The system can use diffuse reflectance spectroscopy, fluorescence spectroscopy and Raman spectroscopy for the detection of cancerous tissue, such as tissue margin assessment.

    See patent
  • Portable Raman diagnostic system

    Issued US US20120035442 A1

    The present invention further relates to the selection of the specific filter combinations, which can provide sufficient information for multivariate calibration to extract accurate analyte concentrations in complex biological systems. The present invention also describes wavelength interval selection methods that give rise to the miniaturized designs. Finally, this invention presents a plurality of wavelength selection methods and miniaturized spectroscopic apparatus designs and the necessary…

    The present invention further relates to the selection of the specific filter combinations, which can provide sufficient information for multivariate calibration to extract accurate analyte concentrations in complex biological systems. The present invention also describes wavelength interval selection methods that give rise to the miniaturized designs. Finally, this invention presents a plurality of wavelength selection methods and miniaturized spectroscopic apparatus designs and the necessary tools to map from one domain (wavelength selection) to the other (design parameters). Such selection of informative spectral bands has a broad scope in miniaturizing any clinical diagnostic instruments which employ Raman spectroscopy in particular and other spectroscopic techniques in general.

    See patent

Courses

  • Introduction to Monte Carlo Methods

    -

  • Mathematical Methods of Physics I

    PHY510

  • Mathematical Methods of Physics II

    PHY610

  • Statistical Physics I

    PHY525

  • Statistical Physics II

    PHY625

Honors & Awards

  • Especially Strong Year (ESY) Award at Dun & Bradstreet (2018)

    Dun & Bradstreet

    Especially Strong Year (ESY) Award in recognition of exceptional performance in 2018. Dun & Bradstreet is committed to recognizing and rewarding team members who execute, deliver results and make a significant impact on our strategy

  • Excellence@EMC - EMC Excellence Silver Award at Global Presales vSE Conference

    EMC Corporation

    The Silver Award is for individuals and teams whose extra efforts exude commitment and demonstrates extraordinary dedication toward the success of the business critical event (vSE Conference), project, or initiative. These achievements will have an obvious, positive impact on business results and customer needs. They may also be characterized by positive cross-functional and/or financial impact.

  • Tony B. Academic Award (2012 and 2013)

    SLAS

    The Tony B. Academic Award honors Tony Beugelsdijk, Los Alamos National Laboratory, an Association for Laboratory Automation (ALA) co-founder who passed away in August, 2009. This award recognizes up-and-coming researchers who have demonstrated outstanding achievement in laboratory science and technology.

  • Young Investigator

    Bioanalysis Journal

    Young Investigator Award recognizes and promotes the work of highly-talented early-career researchers in Bio-Analytics field.

  • Junior Research Fellow

    Department of Science and Technology, Government of India

  • Merit Award for Academic Excellence (Telugu Vignana Paritoshikam)

    State Government of Andhra Pradesh

  • Student Senator (2002 to 2007)

    Graduate Student Association, University of Rhode Island

    The Graduate Student Association (GSA) is a government body maintained by and for the graduate students of the University with the purpose of enhancing the academic, intellectual, and social opportunities of its members. Officers and members of the GSA Senate, who are elected annually from the entire graduate student body, distribute GSA funds to graduate students and other qualifying groups, organize social events, and serve as graduate student representatives on University-wide committees.

Test Scores

  • GRE Quant

    Score: 800/800

Languages

  • English

    Native or bilingual proficiency

  • Telugu

    Native or bilingual proficiency

  • Hindi

    Native or bilingual proficiency

  • Sanskrit

    Limited working proficiency

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